PE/PP Plastic Bottle Sealing Machine Intravenous Therapy Bfs Filling Line/Ultrasonic Soft Tubes Filling Sealing Machine for Healthcare and Pharmaceutical

After-sales Service: Field Installation, Commissioning and Training
Warranty: 1 Year
Type: Volumetric Filling Machine

Product Description

Basic Information
Model NO.
Customized IVEN -1
Automatic Grade
Automatic
Material Type
Granular
Filling Valve Head
Multi-Head
Dosing Device
Capacity Cup
Filling Principle
Pressure
Structure
Rotary
Packaging Material
Plastic (PE/PP)
Power Source
3p/AC380V
Installed Power
42kw
Manufacturing Standard
cGMP
Origin
China
Product Description

BFS Machine Manufacturing Machine / Blowing Filling Sealing Production Line

The BFS is a dedicated state of the art system, enabling primary packaging of bulk pharmaceutical solutions into plastic containers of polypropylene or high density polyethylene or low density PE, using a Blow-Fill-Seal (BFS) technology.

The BFS processes are performed automatically in a single machine under a controlled environment (sterile filtered air-shower):

  • Extrusion of plastic granulate into a parison at high temperatures
  • Blow-moulding of parison into a container with sterile-filtered air
  • Filling of sterile-filtered solution
  • Hermetic sealing of filled container
BFS Machine
BFS Production Line

This Filling unit assembly is composed of filling nozzles, the manifold with filling valves, the assembly for sterile air shower around the nozzles, the guide bars and the drive. It is possible to provide special cylinder drive for shifting the nozzles up and down, offering a safe and clean assembly right above the filling nozzles.

Filling Unit
Nozzle Assembly
Our Advantages
  • GMP Compliance: Design, MOC, manufacture, assembly, and debugging meet the requirements of new GMP standards.
  • Advanced Performance: Unique and reasonable structure with stable and reliable performance.
  • Versatile Specifications: Applicable for 0.2ml-1000ml plastic bottles based on user requirements.
  • High Capacity: Production capacity ranges from 1000-18000 BPH (Customized).
  • Precision Filling: Filling accuracy is maintained at ≤ ±1%.
  • Integrated Efficiency: Combines bottle making, filling, and capping in a compact structure, reducing cleanroom area and energy consumption.
  • Servo Control: Low-speed long-screw extruder driven by a specially designed servo motor reduces thermal stress and ensures accurate preform sizing.
Advantage 1
Advantage 2
Advantage 3
Product Parameters
NO Project Parameters of BFS Machine
1Size (L×W×H)3500*1400*2800mm
2Weight4.5T
3DeflasherInternal punching
4Power Source3P/AC380V
5Installed Power42Kw
6Power Rating30Kw
7Machine StructureDark side white side unseperation
8Packing MaterialsPE/PP
9Specification1ml-50ml
10Capacity3000 pcs/h (1ml); 1500 pcs/h (10ml)
11Filling Accuracy±1.5% (based on 5ml)
12Manufacturing StandardcGMP
13Compress Airno oil, no water @ 8bar, 200NL/min
14Cooling Water8-12ºC (pure water) @ 4bar, 2m³/h
15Pure Steam125ºC @ 2bar, 25kg/h
Production Showcase
Gallery 1
Gallery 2
Gallery 3
Gallery 4
Gallery 5
Gallery 6
Frequently Asked Questions
What is Blow-Fill-Seal (BFS) technology?
BFS technology is an advanced manufacturing process where the container is formed, filled, and sealed in one continuous automated system under a sterile environment, minimizing contamination risks.
What materials are suitable for this machine?
The machine is designed to work with pharmaceutical-grade plastic granulates, specifically Polypropylene (PP), High-Density Polyethylene (HDPE), and Low-Density Polyethylene (LDPE).
Does the machine meet international pharmaceutical standards?
Yes, the design, manufacturing, and assembly of the BFS machine strictly adhere to cGMP standards and IEC electrical safety requirements.
What is the typical filling accuracy of the BFS line?
The machine provides high precision with a filling accuracy of ≤ ±1% to ±1.5%, depending on the specific volume and medium being filled.
Can the production capacity be customized?
Yes, the production capacity is customizable, ranging from 1,000 to 18,000 bottles per hour (BPH) based on the client's specific requirements and bottle sizes.
What bottle sizes can this machine handle?
The BFS machine is versatile and can be configured for a wide range of specifications, typically from 0.2ml up to 1000ml plastic bottles.

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